Do these cholesterol drugs help prevent strokes and heart problems?
Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
PCSK9 inhibitors reduce stroke risk significantly even in people with no prior heart disease.
Many assume such potent drugs are only useful after a heart event, but this shows major preventive power in healthy-seeming high-risk patients.
Practical Takeaways
Talk to your doctor about PCSK9 inhibitors if you're at high risk for heart disease but haven't had an event yet.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
PCSK9 inhibitors reduce stroke risk significantly even in people with no prior heart disease.
Many assume such potent drugs are only useful after a heart event, but this shows major preventive power in healthy-seeming high-risk patients.
Practical Takeaways
Talk to your doctor about PCSK9 inhibitors if you're at high risk for heart disease but haven't had an event yet.
Publication
Journal
International journal of clinical pharmacology and therapeutics
Year
2024
Authors
Kwang-hee shin, Hye Duck Choi
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Claims (4)
Taking a drug called evolocumab can lower the chance of having a first major heart problem by 25% in people at high risk who’ve never had a heart attack or stroke before.
Taking certain cholesterol drugs called evolocumab or alirocumab may help lower the chance of heart problems, whether you've already had heart issues or are just trying to prevent them.
Taking certain cholesterol drugs called evolocumab or alirocumab might lower the chance of having a stroke, whether you've already had heart problems or not.
Taking cholesterol drugs called evolocumab or alirocumab doesn’t seem to raise your risk of bleeding in the brain — the numbers show it’s about the same as not taking them.