Back to Study: Effect of dietary additives on intestinal permeabi...
correlational
neutral effect
A common food additive called titanium dioxide nanoparticles doesn't seem to make the gut more leaky in fruit flies or human gut cells in a lab setting.
Scientific Claim
Titanium dioxide nanoparticles (a common food additive) showed minimal effects on intestinal permeability in both Drosophila melanogaster and human intestinal cell co-cultures.
Source Excerpt
“TiO2 NP had minor and variable effects on intestinal permeability and survival when tested using our in vivo Drosophila feeding conditions (Figs 1C,D and 3C,D). Similar results were seen in the in vitro model, with no change in permeability upon exposure to TiO2 (Fig. 2A).”
Evidence from Studies
Supporting Studies
Effect of dietary additives on intestinal permeability in both Drosophila and a human cell co-culture
Cannot Determine
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Evidence Assessment
Supported
The study measured Smurfing in flies and Lucifer Yellow permeability in human cells with TiO2 exposure, finding no significant changes compared to controls.