A drug called evolocumab, when given every two weeks, cuts bad cholesterol by more than 60% in people at high risk for heart problems — and that result has shown up consistently in several major...

A drug called alirocumab, given as a 75mg shot every couple of weeks, lowered bad cholesterol by almost half in people at high risk for heart problems over six months — a bit less than another similar drug, evolocumab.

For people with diabetes who don’t have serious artery disease, adding a drug called evolocumab to their usual cholesterol medicine lowers bad cholesterol a lot — down to 52, compared to 111 without it — after a year.

Even if someone with heart disease is already taking cholesterol-lowering drugs and their cholesterol is pretty low, adding a drug called evolocumab can still help protect their heart.

For people with diabetes or clogged arteries who haven’t had a heart attack or stroke yet, taking a drug called evolocumab every two weeks can lower their chance of having a first heart attack, stroke, or heart-related death by about 25% over nearly 5 years.

For people with heart disease who are already taking cholesterol-lowering drugs, adding a medicine called evolocumab can lower their chance of having a heart attack, stroke, or other serious heart problems by about 15% over two years.