A small dose of whey protein hydrolysate made a key muscle-building signal stronger in rats than regular whey protein or no protein.
Scientific Claim
In rats, whey protein hydrolysate at 0.5 g/kg body weight was associated with higher phosphorylation of 4E-BP1 at Thr37/46 compared to the control group 60 minutes post-exercise, whereas intact whey protein at the same dose was not.
Original Statement
“At a dose of 0.5 g/kg BW, the phosphorylated 4E-BP1 levels only in the WPH group were significantly higher than in the control group (p < 0.05).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design supports association claims. The phrasing correctly uses 'associated' and specifies comparison to control.
Evidence from Studies
Supporting (1)
Effects of whey protein hydrolysate ingestion on post-exercise muscle protein synthesis compared with intact whey protein in rats