The Claim

In active men aged 18–40 undergoing resistance training, daily supplementation with 3 g of micronized creatine monohydrate (KleanCREATINE™) for eight weeks reduces perceived exertion during workouts by 26.4%, which is significantly greater than the 13.46% reduction observed with a standard marketed creatine monohydrate formulation.

Source: Comparative Efficacy and Pharmacokinetic Parameters of Micronized Creatine Monohydrate (KleanCREATINE™) in Active Men: A Randomized, Controlled Clinical Study

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
75score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Among active men aged 18–40 who lift weights, taking 3 grams of a specific micronized creatine monohydrate supplement daily for eight weeks reduces how hard they feel their workouts are by 26.4%, compared to a 13.46% reduction with a different creatine supplement.

See the scientific wording

In active men aged 18–40 undergoing resistance training, daily supplementation with 3 g of micronized creatine monohydrate (KleanCREATINE™) for eight weeks reduces perceived exertion during workouts by 26.4%, significantly more than the 13.46% reduction seen with a standard marketed creatine monohydrate formulation.

Why this might work

When creatine is absorbed into muscle cells, it helps rebuild ATP faster during intense exercise, which lowers the buildup of fatigue-causing acids and signals to the brain that the body is less tired, allowing the person to feel less exertion.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Comparative Efficacy and Pharmacokinetic Parameters of Micronized Creatine Monohydrate (KleanCREATINE™) in Active Men: A Randomized, Controlled Clinical Study

    This study found that men who took a special finely ground version of creatine felt 26% less tired during workouts than those who took the regular kind — even though both took the same dose. So yes, the fancy version worked better.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.