In active men aged 18–40 undergoing resistance training, daily supplementation with 3 g of micronized creatine monohydrate (KleanCREATINE™) for eight weeks increases arm circumference by 12.65% and thigh circumference by 10.36%, significantly more than the 6.65% and 4.65% increases observed with a standard marketed creatine monohydrate formulation.

Finely ground creatine enters the bloodstream faster and more completely than regular creatine, so more of it gets into muscle cells. This pulls water into the muscles, making them swell, which signals the cells to build more muscle protein. At the same time, the extra creatine helps muscles recover energy faster between lifts, allowing more total work to be done, which further stimulates muscle growth.