Adding a collagen scaffold to stitched-up knee ligaments in pigs didn't make the knee wobble less when bent at different angles compared to just stitching it up.
Scientific Claim
In Yucatan minipigs with ACL transection and suture repair, collagen scaffold augmentation did not significantly improve anteroposterior knee laxity at 30° flexion (mean difference 1.7 mm, p=0.07), 60° flexion (mean difference 0.4 mm, p=0.66), or 90° flexion (mean difference 0.1 mm, p=0.85) compared to suture repair alone.
Original Statement
“The addition of the collagen scaffold to suture repair of a transected ACL did not significantly improve the mean anteroposterior knee laxity [SCAFFOLD vs. SUTURE: 6.1 ± 1.4 vs. 4.4 ± 2.0 mm (p=0.07), 8.1 ± 2.0 vs. 7.6 ± 2.0 mm (p=0.66), and 6.2 ± 1.2 vs. 6.1 ± 1.8 mm (p=0.85) at 30°, 60°, and 90° flexion, respectively].”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
The claim states statistical results (p-values and mean differences) without implying causation or human applicability. 'Did not significantly improve' accurately reflects the data.
Evidence from Studies
Supporting (1)
Collagen scaffold supplementation does not improve the functional properties of the repaired anterior cruciate ligament