The scaffold didn't make the repaired ligament stronger in pigs—it broke at the same force as stitches alone.

Scientific Claim

In Yucatan minipigs, collagen scaffold augmentation of ACL suture repair did not significantly improve maximum failure load (mean difference 17.6 N, p=0.86) compared to suture repair alone.

Original Statement

“Maximum tensile load (N) 362.7±117.9 380.3±181.8 17.6±264.2 0.86”

From study:Collagen scaffold supplementation does not improve the functional properties of the repaired anterior cruciate ligament

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

definitive

Can make definitive causal claims

Assessment Explanation

The claim precisely reports the numerical difference and p-value from tensile testing without overgeneralizing.

Evidence from Studies

Supporting (1)

Collagen scaffold supplementation does not improve the functional properties of the repaired anterior cruciate ligament

Randomized Controlled Trial

Animal

2010 Jun

Contradicting (0)

No contradicting evidence found

Source Study

Collagen scaffold supplementation does not improve the functional properties of the repaired anterior cruciate ligament

Score: 14

DOI: 10.1002/jor.21071

Similar Assertions

In pigs, adding a collagen scaffold to stitched ACL repairs didn't make the ligament stronger or stiffer than just stitching it.

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Pigs with scaffold-augmented ACL repairs had the same knee movement and stability tests as those with just stitches.

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The collagen scaffold by itself didn't help heal the knee ligament in pigs—other biological factors like platelets might be needed.

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Adding a collagen scaffold to stitched-up knee ligaments in pigs didn't make the knee wobble less when bent at different angles compared to just stitching it up.

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Under the microscope, the healed ligaments in pigs looked the same whether they had a collagen scaffold or not.

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