quantitative
Analysis v1
81
Pro
0
Against

A drug called tesamorelin makes belly fat shrink by 11% in 6 months, while fake pills barely change anything.

Scientific Claim

Administration of tesamorelin results in a statistically significant reduction in visceral adipose tissue volume compared to placebo, with a mean reduction of approximately 11% after 6 months of treatment.

Original Statement

Visceral fat decreased by nearly 11% in the tesamorelin group. Okay, this was compared to less than 1% in the placebo group. Waist circumference went down, trunk fat went down, IGF levels went up...

Context Details

Domain

pharmacology

Population

human

Subject

Tesamorelin

Action

reduces

Target

visceral adipose tissue volume

Intervention Details

Type: drug
Dosage: 2 mg subcutaneous daily
Duration: 6 months

Evidence from Studies

Supporting (3)

81
81

Unknown Title

Randomized Controlled Trial
Human

In a well-run study, people with HIV who took tesamorelin lost about 11% of their dangerous belly fat in 6 months, while those on a dummy pill lost almost none — proving the drug works.

This study shows that giving tesamorelin to people with HIV helps shrink the dangerous belly fat, which is exactly what the claim says.

This study confirms that tesamorelin shrinks belly fat in HIV patients — the exact thing the claim is about.

Contradicting (0)

0
No contradicting evidence found