The Claim
In patients with ST-elevation myocardial infarction, three months of polyphenol supplementation is associated with a significant reduction in the Firmicutes/Bacteroidetes ratio and an increased abundance of butyrate-producing bacteria including Roseburia, Agathobaculum sp., Alistipes finegoldii, and Sellimonas.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In patients who have had a heart attack called STEMI, taking polyphenol supplements for three months is linked to a decrease in the ratio of Firmicutes to Bacteroidetes gut bacteria and an increase in specific butyrate-producing bacteria.
See the scientific wording
In STEMI patients, 3 months of polyphenol supplementation is associated with a significant reduction in the Firmicutes/Bacteroidetes ratio and increased abundance of butyrate-producing bacteria including Roseburia, Agathobaculum sp., Alistipes finegoldii, and Sellimonas, suggesting a shift toward a microbiome profile potentially linked to improved gut barrier function and reduced TMAO production.
Polyphenols feed specific good bacteria in the gut that make butyrate, which strengthens the gut lining and crowds out bad bacteria that produce harmful chemicals. This lowers the ratio of bad to good bacteria and stops the body from making a toxin linked to heart disease.
What the research says
1 studyStudy: Polyphenol-mediated microbiome modulation in STEMI patients: a pilot study
After a heart attack, people who took grape polyphenols for three months had more good gut bacteria that make butyrate and fewer bad ones, which helped keep a harmful substance called TMAO from rising—exactly what the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.