After a week of MOTS-c injections, mice could process insulin better, needing 30% more glucose to keep blood sugar stable during a test.

Pro

Against

Evidence from Studies

Supporting (0)

Community contributions welcome

No supporting evidence found

Contradicting (1)

Community contributions welcome

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Randomized Controlled Trial

Animal

2015 Mar 3

The study says MOTS-c helps mice better use insulin, but it doesn’t say exactly how much, for how long, or in which mice — so we can’t confirm the specific numbers in the claim.

Source Study

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Score: 13

DOI: 10.1016/j.cmet.2015.02.009

Similar Assertions

When mice were given a daily shot of a peptide called MOTS-c, their bodies became better at using sugar for energy and responding to insulin, especially in their muscles.

85%

Diabetic rats given MOTS-c had lower blood sugar levels after fasting, showing better control of glucose.

78%

Obese mice given MOTS-c injections for three days had lower blood sugar levels than mice that didn't receive the treatment.

78%

Obese mice given MOTS-c had lower levels of suberate, a dicarboxylic acid, by 40% compared to untreated mice.

73%

Old mice that got MOTS-c for a week had muscle glucose uptake as good as young mice, reversing age-related insulin resistance.

71%