After eating mostly fat for three days, the pancreas of healthy young men released less insulin right after they drank sugar water, even though their blood sugar went higher.

33

Pro

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Against

Evidence from Studies

Supporting (1)

33

Community contributions welcome

33

Short-term low carbohydrate/high-fat diet intake increases postprandial plasma glucose and glucagon-like peptide-1 levels during an oral glucose tolerance test in healthy men

Cross-Sectional Study

Human

2012 Aug

The study gave men a high-fat, low-carb diet for 3 days and found their bodies released less insulin right after drinking sugar water, which is exactly what the claim says happens.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Short-term low carbohydrate/high-fat diet intake increases postprandial plasma glucose and glucagon-like peptide-1 levels during an oral glucose tolerance test in healthy men

Score: 33

DOI: 10.1038/ejcn.2012.58

Similar Assertions

After eating a high-fat, low-carb diet for three days, the pancreas releases less insulin right after you drink sugar — even though blood sugar goes up.

33

0

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After eating just three days of mostly fatty food instead of carbs, healthy young men had higher blood sugar spikes when they drank a sugary drink, meaning their bodies handled sugar less efficiently.

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When healthy young men ate the same number of calories but swapped carbs for fat for just three days, their body’s response to sugar changed—blood sugar went up, insulin came out slower, and a gut hormone went up.

33

0

84%

Eating very low-carb, high-fat food for just three days makes blood sugar spike higher after drinking a sugary drink, compared to eating a normal diet.

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0

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If you swap out a small amount of fatty foods for sugary or starchy ones for six weeks, your body releases less insulin after eating—even though your blood sugar goes up the same—which might mean your pancreas isn’t working as well.

33

0

78%