After losing weight, the extent to which metabolism slows down can help predict how much weight a person will regain, but this metabolic slowdown has a smaller impact on weight regain than how many...
Mechanism
Synthesis from 1 study
People who burn more calories at rest before dieting are more likely to regain weight because their bodies naturally signal a stronger urge to eat more, leading them to consume extra food that gets stored as muscle and fat, as shown in the study with DOI 10.1038/s41366-021-00748-y. This effect is...
Most probable mechanism
People who naturally burn more calories at rest before dieting tend to regain more weight afterward because their bodies signal a stronger need to eat more, leading them to consume extra food that gets stored as muscle and fat, as shown in the study with DOI 10.1038/s41366-021-00748-y.
Higher pre-diet 24-hour energy expenditure under sedentary, eucaloric conditions reflects elevated basal metabolic rate and/or digestive efficiency, creating a persistent energy demand relative to intake.
This elevated energy demand activates central appetite-regulating pathways, increasing orexigenic drive and reducing satiety signaling during post-diet free-living conditions.
Increased orexigenic drive leads to hyperphagia, resulting in sustained positive energy balance after caloric restriction ends.
Excess energy intake is preferentially stored as fat-free mass and fat mass, with fat-free mass restoration being the dominant contributor to total weight regain.
Evidence from Studies
Supporting (1)
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