In women aged 45 to 60, daily ingestion of a hyaluronic acid solution (≥1 MDa) in a cascade-fermented organic whole food concentrate for 40 days is associated with a statistically significant increase in skin elasticity (R2 ratio) from 0.616 to 0.697, corresponding to a 13.3% improvement, as measured by Cutometer MPA 580.

When a person drinks a solution containing high-molecular-weight hyaluronic acid, some of it gets broken down by bacteria in the gut into smaller pieces that enter the bloodstream. These pieces travel to the skin, where they trigger skin cells to make more of their own hyaluronic acid. This increases water retention in the deeper layer of the skin, making it plumper and more resilient. At the same time, the hyaluronic acid reduces damage from harmful molecules that break down collagen and elastin, so the skin's internal structure stays strong and springs back after being stretched.