The Claim

In women aged 45 to 60, daily ingestion of a hyaluronic acid solution (≥1 MDa) in a cascade-fermented organic whole food concentrate for 40 days is associated with a 26.4% reduction in periorbital wrinkle depth, as measured by PRIMOS Compact, from 450.28 to 331.35 micrometers.

Source: Ingestion of an Oral Hyaluronan Solution Improves Skin Hydration, Wrinkle Reduction, Elasticity, and Skin Roughness: Results of a Clinical Study

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
44score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

Women aged 45 to 60 who consumed a specific hyaluronic acid supplement daily for 40 days showed a 26.4% decrease in the depth of wrinkles around the eyes, as measured by PRIMOS Compact.

See the scientific wording

In women aged 45 to 60, daily ingestion of a hyaluronic acid solution (≥1 MDa) in a cascade-fermented organic whole food concentrate for 40 days is associated with a 26.4% reduction in periorbital wrinkle depth, as measured by PRIMOS Compact, from 450.28 to 331.35 micrometers.

Why this might work

When hyaluronic acid is swallowed, it passes through the gut where bacteria break it into smaller pieces that enter the bloodstream. These pieces travel to the skin and tell skin cells to make more hyaluronic acid and multiply. More hyaluronic acid in the skin holds more water, plumping the tissue and making it more elastic. At the same time, the hyaluronic acid reduces damage from harmful molecules in the skin, which protects the fibers that keep skin firm. Together, this makes wrinkles around the eyes shallower.

Verified mechanismbased on 1 study

What the research says

1 study

  1. Study: Ingestion of an Oral Hyaluronan Solution Improves Skin Hydration, Wrinkle Reduction, Elasticity, and Skin Roughness: Results of a Clinical Study

    This study found that middle-aged women who took a daily drink containing hyaluronic acid and other nutrients for 40 days had noticeably smoother skin around their eyes. The results match what the claim says — the supplement helped reduce fine wrinkles.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.