The Claim

A single 0.35 g/kg dose of creatine administered during sleep deprivation results in peak cognitive benefits approximately 4 hours post-ingestion, with effects persisting for up to 9 hours, indicating a delayed but sustained impact on brain energy metabolism and cognitive function.

Source: Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
66score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

Taking 0.35 grams of creatine per kilogram of body weight during sleep deprivation improves cognitive performance, with the strongest effects occurring about 4 hours after taking it and lasting up to 9 hours, likely due to sustained changes in how the brain uses energy.

See the scientific wording

The cognitive benefits of a single 0.35 g/kg creatine dose during sleep deprivation peak at approximately 4 hours post-ingestion and persist for up to 9 hours, suggesting a delayed but sustained effect on brain energy metabolism and cognitive function.

What the research says

1 study
  1. Study: Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation

    This study found that taking a single dose of creatine helps your brain work better even when you're sleep-deprived, and the good effects last for many hours — starting a bit later but sticking around.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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