The Claim
Allopurinol reduces serum uric acid concentration by enhancing renal excretion of uric acid.
What the research says
Not yet evaluated
We are still looking at what the research says.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Allopurinol decreases the amount of uric acid in the blood by increasing how much uric acid the kidneys remove through urine.
See the scientific wording
Allopurinol lowers serum uric acid by increasing renal excretion.
Allopurinol turns into a compound called oxypurinol in the liver, which blocks the enzyme that makes uric acid. Less uric acid is made, and the oxypurinol that remains in the blood gets reabsorbed by the kidneys in the same way as uric acid, which keeps more oxypurinol in the body longer. This stronger and longer-lasting block of uric acid production lowers the amount of uric acid in the blood.
Score breakdown, mechanism chain, raw evidence, ideal studies needed
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.