The Claim

In 19 adults with elevated cardiometabolic risk, daily supplementation with 5g of TOTUM-63 for 8 weeks was associated with statistically significant reductions in triglycerides, total cholesterol, LDL cholesterol, and total-C/HDL-C ratio (all p<0.05).

Source: 725-P: TOTUM-63 (T63), a Novel Plant-Based Polyphenol-Rich Substance, Improves Glucose Homeostasis and Modulates Gut Microbiota Diversity among Adults at Increased Cardiometabolic Risk

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
20score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In a group of 19 adults with high cardiometabolic risk, taking 5 grams of TOTUM-63 daily for 8 weeks was linked to measurable decreases in triglycerides, total cholesterol, LDL cholesterol, and the total-C/HDL-C ratio.

See the scientific wording

In 19 adults with elevated cardiometabolic risk, 8 weeks of daily 5g TOTUM-63 supplementation was followed by statistically significant reductions in triglycerides, total cholesterol, LDL cholesterol, and total-C/HDL-C ratio (all p<0.05), suggesting a potential association between this supplement and improved lipid profiles in this population.

Why this might work

Plant compounds in the supplement feed beneficial gut bacteria, which produce substances that strengthen the gut lining and reduce leakage of harmful molecules into the blood. This lowers chronic inflammation and triggers the release of hormones that improve how the body handles sugar and fat, leading to less fat being made and stored in the liver and bloodstream.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: 725-P: TOTUM-63 (T63), a Novel Plant-Based Polyphenol-Rich Substance, Improves Glucose Homeostasis and Modulates Gut Microbiota Diversity among Adults at Increased Cardiometabolic Risk

    In a small study, people with higher risk for heart disease took a plant-based supplement every day for 8 weeks, and their bad fats in the blood went down — exactly what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.