Strong Support
causal
Taking a supplement called betaine can lower a substance in your blood called homocysteine, which is linked to a higher chance of getting Alzheimer’s—so this supplement might help protect your brain.
78
0
Evidence from Studies
Supporting (5)
78
Community contributions welcome
68
Betaine supplementation decreases plasma homocysteine in healthy adult participants: a meta-analysis.
Systematic Review With Meta-Analysis
Human
2013 Mar65
Betaine supplementation decreases plasma homocysteine in healthy adult participants: a meta-analysis.
Systematic Review With Meta-Analysis
Human
2013 Mar33
Effects of betaine supplementation on cardiovascular markers: A systematic review and Meta-analysis
Systematic Review With Meta-Analysis
Human
20227
Alleviation of hepatic fat accumulation by betaine involves reduction of homocysteine via up-regulation of betaine-homocysteine methyltransferase (BHMT).
Cohort Study
Animal & In Vitro
2016 Aug 26Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.