Blocking a specific enzyme in fruit flies and tiny worms helps them live longer, suggesting that changing how their bodies process a certain nutrient can slow aging in these animals.

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Evidence from Studies

Supporting (1)

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Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan.

Narrative Review

Animal

2020 Apr

The study talks about blocking a pathway that starts with a chemical called tryptophan, and this helps fruit flies and worms live longer. That’s what the claim is about, even if it doesn’t name the exact method used.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan.

Score: 1

DOI: 10.1016/j.exger.2020.110841

Similar Assertions

When mice are genetically changed so they don’t break down a certain nutrient (tryptophan) as much, it might help them live longer and healthier — and this could mean the same process matters for aging in other animals, including people.

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