In mice, blocking two specific signals in the body (IL-6 and JNK) fixes blood sugar problems, fatty liver, and insulin resistance caused by a keto diet—basically undoing those issues in just 3 days.

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Evidence from Studies

Supporting (1)

13

Community contributions welcome

13

A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice

Cross-Sectional Study

Animal

2023 Mar

The study shows that blocking two specific signals in the liver (IL-6 and JNK) helps reverse blood sugar and liver problems caused by a ketogenic diet in mice, which matches the main point of the claim.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice

Score: 13

DOI: 10.1016/j.molmet.2023.101675

Similar Assertions

In mice, eating a keto diet for just 3 days seems to raise a certain protein linked to inflammation, especially from belly fat, which might lead to liver problems and trouble using insulin.

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In mice, going on a keto diet for just 3 days seems to make their livers less responsive to insulin—even though their blood sugar is lower—suggesting early signs of metabolic problems.

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76%