In mice, going on a keto diet for just 3 days seems to make their livers less responsive to insulin—even though their blood sugar is lower—suggesting early signs of metabolic problems.

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Evidence from Studies

Supporting (1)

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13

A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice

Cross-Sectional Study

Animal

2023 Mar

The study shows that a keto diet in mice leads to blood sugar problems and liver insulin resistance, which matches the main idea of the claim.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice

Score: 13

DOI: 10.1016/j.molmet.2023.101675

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If you're an adult with mild type 2 diabetes, switching to a keto diet for 12 weeks might lower a fat in your blood linked to liver fat, more than a low-fat diet would.

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