Blood pressure is made up of three things: how much blood the heart pumps, how much fluid is in the blood, and how tight the blood vessels are.
Scientific Claim
Blood pressure is determined by cardiac output, blood volume, and vascular resistance; an increase in any of these factors elevates blood pressure.
Original Statement
“Blood pressure is the product of three forces and three forces only. The first one is cardiac output, which is how much blood your heart pushes out with each beat. The second one is blood volume, which is the total amount of fluid circulating in your system. The third one is vascular resistance, which is how relaxed or constricted your arteries are at any given moment.”
Context Details
Domain
cardiology
Population
human
Subject
cardiac output, blood volume, and vascular resistance
Action
determine
Target
blood pressure
Intervention Details
Evidence from Studies
Supporting (2)
Short‐Chain Fatty Acid Butyrate Is an Inotropic Agent With Vasorelaxant and Cardioprotective Properties
A compound produced by gut bacteria was found to increase heart output and reduce blood vessel resistance, which can raise blood pressure.
Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility
This study found that a specific type of ketone body increases heart output and reduces blood vessel resistance, which can raise blood pressure.
Contradicting (2)
Increasing heart output can improve blood flow to the brain without raising blood pressure in certain conditions.
A certain body position can decrease heart output and increase blood vessel resistance in newborns, which can affect blood pressure.