Cellulite isn’t caused by fat — it’s caused by fibrous bands pulling skin down, and one drug could break those bands, but it was pulled for side effects.

“There is actually no treatment for cellulite, but I think in your post it was interesting because you did go through like the pathogenesis of cellulite, and how it happens, even the skinny people have it, and the kind of the hormonal connection and what we think might be happening. There was a really interesting drug that was available, hopefully will come back on to market, that was looking really promising because I don't know if... Have you heard something called Dupuytren's contracture? No? So that's a neurological disease where people get contractions of the I guess tendons... tendons in the hands so that they have like a claw hand. So these contract and they go like this, it goes like this. So, in that condition, a drug was being used to almost like dissolve that those contracted tendons so that the hand would open. Don't ask me about any specifics about that, but that drug had a funky name, but it was called “Qwo”, and it was being used for cellulite. QWO. And it was being injected into the areas of cellulite and it was dissolving the netting holding the fat in place, which was getting rid of the cellulite. And it was extremely effective, super effective. It was taken off the market after about a year because it was found to be causing bruising and some post inflammatory pigmentation in those areas.”