Kids with a rare condition called Bardet-Biedl syndrome seem to have problems in a brain-body system that controls sex hormones, which might explain why their testosterone levels are low.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Empty sellae, impaired testosterone secretion, and defective hypothalamic-pituitary growth and gonadal axes in children with Bardet-Biedl syndrome.

Case Report

The study looks at kids with Bardet-Biedl syndrome and finds problems in the brain and hormone system that control testosterone, which supports the idea that these issues cause low testosterone.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Empty sellae, impaired testosterone secretion, and defective hypothalamic-pituitary growth and gonadal axes in children with Bardet-Biedl syndrome.

Score: 3

DOI: 10.1016/S0026-0495(96)90240-1

Similar Assertions

Kids with a rare genetic condition called Bardet-Biedl syndrome sometimes have underactive sex glands, and this might be linked to issues in the brain's hormone control center — meaning their body's hormone system could be involved in how the condition shows up.

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Kids with a rare genetic condition called Bardet-Biedl syndrome have sometimes been found to have a change in the brain area that holds the pituitary gland, which might mean the structure isn't forming normally.

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70%