Too much insulin over time makes blood vessels stiff and unable to relax, making high blood pressure worse.

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Investigating the Effect of a Multicomponent Exercise Program on Adropin, Endothelial Function, Insulin Resistance, and Sleep Quality in Overweight Older Adults (a Link With Physiological Indexes and Sleep Quality): Results of a Randomized Controlled Study.

Randomized Controlled Trial

Human

This study found that a combination of exercises can improve insulin sensitivity, blood vessel function, and sleep quality in older adults with excess weight.

Comparison of the Effect of Aerobic Exercise Versus Yoga on Endothelial Function and Insulin Resistance in Type 2 Diabetic Patients

Randomized Controlled Trial

Human

2025 Aug

This study found that exercise, whether aerobic or yoga, can improve blood vessel function and insulin sensitivity in people with type 2 diabetes.

Similar Assertions

In healthy adults, insulin doesn't make blood vessels relax more when nitric oxide is already at work — meaning insulin probably doesn't improve blood flow by boosting the muscle's response to nitric oxide.

77%

Insulin helps blood vessels relax better when the signal comes from the vessel lining, but not when the signal bypasses it—meaning insulin probably boosts the lining's ability to release a blood-vessel-relaxing chemical called nitric oxide.

76%

When your body doesn't have enough nitric oxide—a molecule that helps blood vessels relax—it seems to make a group of related health problems like diabetes, kidney issues, and heart trouble get worse.

71%

In rats, eating a diet that's a bit high in fat or salt messes up blood vessel function in muscles before the muscle cells themselves become resistant to insulin — and that blood vessel problem alone can slow down how much sugar the muscles take in.

70%