Taking creatine or nicotinamide before damage might help protect skin cells from stress and aging by reducing harmful molecules called free radicals.

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Pro

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Against

Evidence from Studies

Supporting (1)

4

Community contributions welcome

4

Creatine and Nicotinamide Prevent Oxidant-Induced Senescence in Human Fibroblasts

Cross-Sectional Study

In Vitro

2021 Nov 16

The study found that creatine and nicotinamide help protect skin cells from damage caused by harmful molecules, which supports the idea that they act as antioxidants to prevent aging in these cells.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Creatine and Nicotinamide Prevent Oxidant-Induced Senescence in Human Fibroblasts

Score: 4

DOI: 10.3390/nu13114102

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