Taking creatine or nicotinamide before damage might help protect skin cells from stress and aging by reducing harmful molecules called free radicals.

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Creatine and Nicotinamide Prevent Oxidant-Induced Senescence in Human Fibroblasts

Cross-Sectional Study

In Vitro

2021 Nov 16

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Creatine and Nicotinamide Prevent Oxidant-Induced Senescence in Human Fibroblasts

Score: 4

DOI: 10.3390/nu13114102

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