How Creatine and Nicotinamide Protect Skin Cells from Aging
Creatine and Nicotinamide Prevent Oxidant-Induced Senescence in Human Fibroblasts
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Post-treatment with creatine or nicotinamide had no effect on senescence markers.
Most people assume anti-aging treatments work best after damage—like repairing wrinkles—but this shows protection only works *before* the insult.
Practical Takeaways
Consider taking creatine or nicotinamide supplements daily if you're concerned about skin aging, especially if you're frequently exposed to sun or pollution.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Post-treatment with creatine or nicotinamide had no effect on senescence markers.
Most people assume anti-aging treatments work best after damage—like repairing wrinkles—but this shows protection only works *before* the insult.
Practical Takeaways
Consider taking creatine or nicotinamide supplements daily if you're concerned about skin aging, especially if you're frequently exposed to sun or pollution.
Publication
Journal
Nutrients
Year
2021
Authors
A. S. Mahajan, V. Arikatla, A. Thyagarajan, Tetyana Zhelay, R. Sahu, M. Kemp, D. Spandau, J. Travers
Related Content
Claims (5)
Taking creatine or nicotinamide before skin cells are stressed by harmful molecules might help keep them talking to neighboring skin cells, which could support skin health when under stress.
Taking creatine or nicotinamide before damage from hydrogen peroxide might help skin cells stay healthier longer by reducing signs of aging in the lab.
Taking creatine or nicotinamide before damage might help protect skin cells from stress and aging by reducing harmful molecules called free radicals.
Taking creatine or nicotinamide before skin cells are stressed might help reduce inflammation, based on lab studies with human skin cells.
After skin cells are damaged, taking creatine or a form of vitamin B3 doesn’t seem to help them recover or become less aged, based on lab tests.