How Creatine and Nicotinamide Protect Skin Cells from Aging
Creatine and Nicotinamide Prevent Oxidant-Induced Senescence in Human Fibroblasts
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
This study checks if two energy-boosting chemicals can stop skin support cells from aging too fast when stressed by harmful molecules.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 54 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
This study checks if two energy-boosting chemicals can stop skin support cells from aging too fast when stressed by harmful molecules.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 54 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Mahajan AS, Arikatla VS, Thyagarajan A, Zhelay T, Sahu RP, Kemp MG, Spandau DF, Travers JB
Related Content
Claims (5)
Taking creatine or nicotinamide before skin cells are stressed by harmful molecules might help keep them talking to neighboring skin cells, which could support skin health when under stress.
Taking creatine or nicotinamide before damage from hydrogen peroxide might help skin cells stay healthier longer by reducing signs of aging in the lab.
Taking creatine or nicotinamide before damage might help protect skin cells from stress and aging by reducing harmful molecules called free radicals.
Taking creatine or nicotinamide before skin cells are stressed might help reduce inflammation, based on lab studies with human skin cells.
After skin cells are damaged, taking creatine or a form of vitamin B3 doesn’t seem to help them recover or become less aged, based on lab tests.