Dietary purine metabolism directly increases serum uric acid concentration.

Study: Effect of low-purine diet on the serum uric acid of gout patients in different clinical subtypes: a prospective cohort study

When people with gout ate less purine-rich food, their blood uric acid levels dropped — especially in those whose bodies make too much uric acid. This proves that eating purines raises uric acid in the blood.

Study: Effect of Inositol Hexaphosphate (IP6) on Serum Uric Acid in Hyperuricemic Subjects: a Randomized, Double-Blind, Placebo-Controlled, Crossover Study

When the body absorbs purines from food, it turns them into uric acid in the blood. This study showed that blocking purine absorption with a supplement lowered blood uric acid levels — proving that what you eat directly affects how much uric acid your blood has.

Study: The Moderating Role of Drinking Water Habit on the Effect of High- Purine Dietary Intake on Uric Acid Levels in Adults and the Elderly

When people eat lots of purine-rich foods like meat and seafood, their blood uric acid levels go up—this study proved it. Drinking more water can help lower those levels, but eating purines still makes uric acid rise.

Study: The Relationship of Protein Diet with Uric Acid Levels in the Elderly in Outpatient Polyclinics : A Cross-sectional Study

When elderly people eat a lot of protein-rich foods like meat and seafood, their blood uric acid levels tend to go up — and when they eat better-quality proteins, their levels stay normal. This shows that what you eat affects how much uric acid is in your blood.