Doctors see noticeable improvements in the belly shape of HIV patients taking tesamorelin, while those on a dummy pill show no change.
Scientific Claim
Physician-rated belly profile improves significantly (P = 0.02) in HIV-infected patients with abdominal fat accumulation treated with tesamorelin compared to placebo.
Original Statement
“Patient rating of belly appearance distress (P = 0.02) and physician rating of belly profile (P = 0.02) were significantly improved in the tesamorelin vs. placebo-treated groups.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
The study is a randomized controlled trial with a control group, which allows for causal inference. The verb 'improves' is appropriate for this design.
Evidence from Studies
Supporting (1)
Unknown Title
Doctors noticed that HIV patients on this drug looked like they had less belly fat compared to those on a dummy pill, and the difference was real and statistically significant.