Medicines like liraglutide, semaglutide, and tirzepatide can help people with extra weight lose pounds and improve their blood sugar, liver health, cholesterol, and blood pressure.

Some diabetes drugs like liraglutide, semaglutide, and dulaglutide may help protect the heart and lower the chance of serious heart problems in people with type 2 diabetes who already have heart disease — and this benefit might not just be because they lower blood sugar.

These diabetes and weight-loss drugs might help prevent or lessen health problems caused by obesity, like heart disease or diabetes.

If someone has had weight-loss surgery but isn’t losing enough weight—or gains it back—taking semaglutide seems to help them lose more weight than if they took liraglutide, and they’re over twice as likely to lose 10% or more of their body weight.

Some diabetes and weight-loss drugs, like tirzepatide, can help people lose a lot of weight—up to nearly 18% more than a fake treatment over a year and a half—especially in those without diabetes, and they might also improve overall health.

When a drug like semaglutide turns on certain brain and body signals, it helps people feel fuller, eat less, and lose about 15% of their body weight on average.