Eating a lot of sugar like high-fructose corn syrup makes your liver produce more fat than eating a lot of fatty foods does, and this happens in both people and mice.

Drinking sugary sodas and other drinks high in fructose may cause your liver to make more fat than when you eat glucose, leading to fatty liver and other health problems.

Eating too much fructose—like the sugar in soda and fruit juice—makes your liver create more fat than other sugars or fatty foods do, and that extra fat can mess with how your body responds to insulin.

Even if your body isn’t using insulin, eating too much fructose (like in sugary drinks) can still trick your liver into making more fat — thanks to special molecular switches called SREBP1c and XBP1s.

Eating too much fructose, like the sugar in soda and sweet snacks, makes your liver create more fat, which raises bad fats in your blood and causes body-wide inflammation, making heart disease more likely.

If you eat less fructose—like the sugar in soda and candy—your liver will make less fat, even if you don’t eat fewer calories overall. This can help reduce fat buildup in the liver, especially if you’re overweight or have fatty liver disease.