Back to Study: Effect of dietary additives on intestinal permeabi...
correlational
negative effect
Eating a lot of sugar causes changes in the structural proteins of the gut wall in fruit flies, making them more disorganized.
Scientific Claim
High sugar consumption is associated with structural changes in the actin cytoskeleton of the posterior midgut in Drosophila melanogaster.
Source Excerpt
“Three weeks of HS, TWEEN 20 or salt feeding led to broken and disorganized actin filaments in a small number of posterior midguts (Fig. 5I-L).”
Evidence from Studies
Supporting Studies
Effect of dietary additives on intestinal permeability in both Drosophila and a human cell co-culture
Cannot Determine
View study →3%
Evidence Assessment
Supported
The study used confocal microscopy to examine actin filaments in fly guts after high sugar exposure, finding disorganization and breaks in the cytoskeleton.