When the inner lining of your arteries gets damaged, bad cholesterol (LDL) slips in and gets oxidized, which tricks your body into sending in immune cells that create fatty buildup—leading to clogged arteries.

This study found that people with a certain version of the ApoB gene have more bad cholesterol, more body stress, and more inflammation — all of which are the exact things that cause artery clogs, just like the claim says.

This study shows that when a harmful cholesterol particle (Lp(a)) gets oxidized, it damages blood vessel lining and causes swelling — but EPA stops that oxidation and reduces the damage. This supports the idea that oxidized cholesterol particles trigger artery plaque buildup.