People with Alzheimer's have blood vessels that don't respond as well to signals that make them open up, even after taking a supplement called nitrate—which normally helps blood flow better—compared to older healthy people and young people.

People with Alzheimer’s might have blood vessel problems for reasons other than just low nitric oxide — something else could be going on too.

In people with Alzheimer’s, blood flow problems in the brain, head, and body get worse as the disease gets worse, and this seems to be tied to a chemical in the blood called nitric oxide—meaning the whole body’s blood vessels might be failing together, not just the brain.

Drinking beetroot juice once doesn't fully fix the blood vessel function in people with Alzheimer's, even though it works better in healthy older adults or young people.

People with worse Alzheimer's disease tend to have lower levels of a substance in their blood that's linked to how well blood flows in the brain and body — and the sicker they are, the lower those levels get.

In people around 78 years old who have Alzheimer’s, the drop in blood flow to the brain and body isn’t because they’re less active, have less muscle, burn fewer calories at rest, or have different levels of carbon dioxide in their blood.