mechanistic
Analysis v1
Strong Support
If you're already fit and lift weights, your muscle cells don't seem to add more helper cells or nuclei, even when you change up your routine—meaning those extra cells might not be needed to make your muscles bigger.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Resistance training variable manipulations are less relevant than intrinsic biology in affecting muscle fiber hypertrophy
Randomized Controlled Trial
Human
2022 MayEven though the muscles got bigger after weight training, the special cells (satellite cells) and nuclei inside the muscle didn’t increase—meaning they probably aren’t needed for muscles to grow in people who already train regularly.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
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