When you lift weights and your muscles get bigger, the number of special repair cells and nuclei inside them tends to go up a bit — but that’s not the whole story; other things are also helping your muscles grow.
Context Details
Domain
exercise_science
Population
human
Subject
Changes in muscle fiber size during resistance training
Action
are moderately associated with
Target
changes in satellite cell and myonuclei content
Intervention Details
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.
Evidence from Studies
Supporting (1)
Resistance training variable manipulations are less relevant than intrinsic biology in affecting muscle fiber hypertrophy
Even though everyone did different types of weight training, people who grew bigger muscles also tended to have more of these special muscle repair cells and extra nuclei — but not everyone did, so other things besides these cells also matter for muscle growth.