Even if someone with heart disease is already taking cholesterol-lowering drugs and their cholesterol is pretty low, adding a drug called evolocumab can still help protect their heart.

74

Pro

0

Against

Evidence from Studies

Supporting (1)

74

Community contributions welcome

74

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

Randomized Controlled Trial

Human

2017 May 4

The study tested evolocumab in heart disease patients on statins and found it lowered bad cholesterol and reduced heart problems, even in those who already had low cholesterol levels.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

Score: 74

DOI: 10.1056/NEJMoa1615664

Similar Assertions

Even if your cholesterol is already pretty low thanks to statins, adding a drug called evolocumab can still help protect your heart and blood vessels.

74

0

99%

For people with heart disease who are already taking cholesterol-lowering drugs, adding a medicine called evolocumab can lower their chance of having a heart attack, stroke, or other serious heart problems by about 15% over two years.

74

0

93%

For people with heart disease who are already taking cholesterol-lowering statins but still have high LDL, adding a drug called evolocumab can lower their chances of having a heart attack, stroke, or other serious heart problems by about 15% over two years.

74

0

92%

For people with heart disease who are already taking cholesterol-lowering drugs, adding a medicine called evolocumab can cut their risk of heart attack, stroke, or dying from heart problems by 20% over about two years.

74

0

91%

Adding a drug called evolocumab to cholesterol-lowering statins can lower the chances of serious heart problems by 20% in people who already have heart disease.

79

0

89%