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Claim
Strong Support
mechanistic
Analysis v3

A chemical from Gila monster spit lasts longer in the body than a natural hormone because it doesn’t break down as quickly, so it keeps working longer to control blood sugar.

14
Pro
0
Against

Evidence from Studies

Supporting (3)

14

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14

The C-terminal extension of exendin-4 provides additional metabolic stability when added to GLP-1, while there is minimal effect of truncating exendin-4 in anaesthetized pigs.

Cross-Sectional Study
Animal
2013 Feb 10
8

In Vitro Metabolic Stability of Exendin-4: Pharmacokinetics and Identification of Cleavage Products

Cross-Sectional Study
Animal & In Vitro
2015
6

Expression and purification of exendin-4, a GLP-1 receptor agonist, in Escherichia coli.

Cross-Sectional Study
Animal & In Vitro
2005 Jun

Contradicting (0)

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No contradicting evidence found

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Similar Assertions

A substance called Exendin-4 works like a longer-lasting version of a natural hormone in your body that helps control blood sugar, so it might help people with type 2 diabetes manage their glucose levels better.

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