For men who lift weights regularly, increasing their weekly training volume by 60% does not lead to greater gains in strength endurance or muscle size compared to sticking with a moderate volume, and...
Mechanism
Synthesis from 1 study
Doing too many workouts floods the muscles with fatigue chemicals that shut down their ability to grow and recover. Even though the body is being pushed harder, it ends up weaker because it can’t repair itself fast enough.
Most probable mechanism
When someone does way more workouts than their body can handle, their muscles get flooded with waste products and stress signals that block the process of building new muscle tissue. This stops growth and makes the muscles weaker over time because they don’t get time to repair.
Increased training volume elevates intramuscular metabolites such as lactate and inorganic phosphate, creating a prolonged state of metabolic stress.
Prolonged metabolic stress suppresses mTORC1 signaling, reducing the rate of muscle protein synthesis.
Reduced protein synthesis fails to offset muscle protein breakdown, resulting in net muscle catabolism and lack of hypertrophy.
Accumulated fatigue and reduced neuromuscular efficiency impair force production during strength endurance tasks.
Evidence from Studies
Supporting (1)
Community contributions welcome
Training Volume Increases Or Maintenance Based On Previous Volume: The Effects On Muscular Adaptations In Trained Males.
Contradicting (0)
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Gold Standard Evidence Needed
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