For people with heart disease who are already taking cholesterol-lowering drugs but still have high bad cholesterol, adding a drug called evolocumab can cut their risk of heart attack, stroke, or...

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

Randomized Controlled Trial

Human

2017 May 4

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

Score: 74

DOI: 10.1056/NEJMoa1615664

Similar Assertions

For people with heart disease who are on cholesterol-lowering drugs, adding a drug called evolocumab doesn’t raise their risk of serious side effects like diabetes or memory problems — the only real downside is a slightly higher chance of soreness at the injection site.

93%

For people with heart disease who are already taking cholesterol-lowering drugs, adding a medicine called evolocumab can lower their chance of having a heart attack, stroke, or other serious heart problems by about 15% over two years.

91%

For people with heart disease who are already taking cholesterol-lowering drugs, adding a medicine called evolocumab can cut their risk of heart attack, stroke, or dying from heart problems by 20% over about two years.

91%

For people with heart disease who are already taking cholesterol-lowering statins but still have high LDL, adding a drug called evolocumab can lower their chances of having a heart attack, stroke, or other serious heart problems by about 15% over two years.

90%

For people with clogged arteries who are already taking cholesterol drugs, adding a medicine called evolocumab can help lower their chance of having a stroke.

89%