Giving mice a supplement called nicotinamide riboside for three months changed the types of gut bacteria they had — some increased, others decreased — which might mean this supplement affects mouse gut health in a specific way.

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Pro

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Against

Evidence from Studies

Supporting (1)

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Community contributions welcome

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Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

Randomized Controlled Trial

Human & Animal

2023 Apr 3

The study gave mice nicotinamide riboside for 12 weeks and found it changed their gut bacteria in the way the claim says—more Lachnospiraceae, less Parasutterella and Bacteroides dorei.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

Score: 45

DOI: 10.1038/s41514-023-00106-4

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