Taking a supplement called nicotinamide riboside for three months doesn’t seem to change the types or balance of gut bacteria in middle-aged, overweight men who don’t have diabetes.

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Pro

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Against

Evidence from Studies

Supporting (1)

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Community contributions welcome

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Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

Randomized Controlled Trial

Human & Animal

2023 Apr 3

The study found that taking nicotinamide riboside for 12 weeks didn’t change the gut bacteria in people, which is exactly what the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

Score: 45

DOI: 10.1038/s41514-023-00106-4

Similar Assertions

Giving mice a supplement called nicotinamide riboside for three months changed the types of gut bacteria they had — some increased, others decreased — which might mean this supplement affects mouse gut health in a specific way.

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77%

Giving rats a special vitamin-like supplement called nicotinamide riboside for three months seems to boost certain 'good' gut bacteria, especially when they're eating a high-fat diet.

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72%

When you add a vitamin called nicotinamide riboside to gut bacteria in a lab, the bacteria turn it into another helpful compound, and this happens the same way in everyone — no matter their age or health condition.

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71%