Analysis Version
vnull
History
Back to Study: Physiological role for nitrate-reducing oral bacte...
descriptive
45
Pro
0
Against

Good bacteria in the mouth turn nitrate into nitrite, and when you kill these bacteria with mouthwash, this conversion stops almost completely.

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study design supports describing the association between mouthwash use and reduced nitrate-reducing capacity. The language 'are necessary for' is slightly strong but appropriate as the study directly measured the capacity reduction.

More Accurate Statement

“In healthy young adults, oral nitrate-reducing bacteria are associated with converting endogenous nitrate to nitrite, as evidenced by near-complete abolition of oral nitrate-reducing capacity after chlorhexidine mouthwash treatment.”

Evidence from Studies

Supporting (1)

45
45

Physiological role for nitrate-reducing oral bacteria in blood pressure control

Randomized Controlled Trial
Human
2013 Feb

Contradicting (0)

0
No contradicting evidence found

Source Study

Physiological role for nitrate-reducing oral bacteria in blood pressure control

Score: 45
DOI: 10.1016/j.freeradbiomed.2012.11.013

Similar Assertions

Using mouthwash that kills bacteria in the mouth makes it harder for the body to convert nitrate to nitrite, which lowers nitrite levels in the blood.

45
0
87%

Using a special mouthwash for a week killed some good bacteria in the mouth, which made less nitrite in saliva and blood, and this caused blood pressure to go up a little bit.

45
0
87%

Bacteria in the mouth help regulate blood pressure by converting nitrate to nitrite, which is part of the body's natural blood pressure control system.

72
53
82%

Using mouthwash that kills mouth bacteria leads to higher levels of nitrate in both saliva and blood.

45
0
81%

Bacteria in the mouth help keep nitrite levels in the blood stable, which is shown by the fact that people with higher nitrite in their saliva also tend to have higher nitrite in their blood.

45
0
81%