Using mouthwash that kills mouth bacteria leads to higher levels of nitrate in both saliva and blood.

Using mouthwash that kills bacteria in the mouth makes it harder for the body to convert nitrate to nitrite, which lowers nitrite levels in the blood.

Bacteria in the mouth help keep nitrite levels in the blood stable, which is shown by the fact that people with higher nitrite in their saliva also tend to have higher nitrite in their blood.

When people start using mouthwash that kills mouth bacteria, their blood pressure can go up within just one day.

Using a special mouthwash for a week made nitrate levels go up in saliva, blood, and urine compared to before using the mouthwash.

Using a special mouthwash for a week killed some good bacteria in the mouth, which made less nitrite in saliva and blood, and this caused blood pressure to go up a little bit.