Analysis Version
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History
Back to Study: Physiological role for nitrate-reducing oral bacte...
descriptive
45
Pro
0
Against

Using a special mouthwash for a week made nitrate levels go up in saliva, blood, and urine compared to before using the mouthwash.

Scientific Claim

In healthy young adults, antiseptic mouthwash use for 7 days increased salivary, plasma, and urinary nitrate concentrations compared to baseline levels.

Original Statement

“In contrast, salivary, plasma, and urinary nitrate concentrations were significantly elevated after mouthwash treatment compared to baseline levels (Figs. 2A–C).”

From study:Physiological role for nitrate-reducing oral bacteria in blood pressure control

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study design supports describing the association between mouthwash use and elevated nitrate levels. The language 'increased' appropriately reflects the observed change without implying causation.

More Accurate Statement

“In healthy young adults, antiseptic mouthwash use for 7 days was associated with increased salivary, plasma, and urinary nitrate concentrations compared to baseline levels.”

Evidence from Studies

Supporting (1)

45
45

Physiological role for nitrate-reducing oral bacteria in blood pressure control

Randomized Controlled Trial
Human
2013 Feb

Contradicting (0)

0
No contradicting evidence found

Source Study

Physiological role for nitrate-reducing oral bacteria in blood pressure control

Score: 45
DOI: 10.1016/j.freeradbiomed.2012.11.013

Similar Assertions

Using mouthwash that kills mouth bacteria leads to higher levels of nitrate in both saliva and blood.

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When people start using mouthwash that kills mouth bacteria, their blood pressure can go up within just one day.

45
0
81%

When people used the special mouthwash, their blood pressure went up within one day and stayed higher for the whole week they used it.

45
0
78%

Using mouthwash that kills bacteria in the mouth makes it harder for the body to convert nitrate to nitrite, which lowers nitrite levels in the blood.

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75%

Using mouthwash that kills mouth bacteria might be bad for heart health because it raises blood pressure by disrupting the body's natural nitrite balance.

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0
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