mechanistic
Analysis v1
Strong Support
Having really low 'bad' cholesterol thanks to how your body naturally processes it doesn’t seem to cause health problems, even over many years.
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0
Evidence from Studies
Supporting (1)
1
Community contributions welcome
1
Clinical and pathophysiological evidence supporting the safety of extremely low LDL levels-The zero-LDL hypothesis.
Narrative Review
Human
2018 Mar-AprThe study looks at people who naturally or through treatment have very low 'bad' cholesterol because their bodies clear it more efficiently, and finds no harm over time, which supports the idea that very low levels are safe.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.