mechanistic
Analysis v1
Strong Support
If you take creatine and get bigger muscles, it’s probably because you’re working out more, not because creatine is changing how your muscles build protein when you’re just sitting around.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Creatine supplementation has no effect on human muscle protein turnover at rest in the postabsorptive or fed states.
Cross-Sectional Study
Human
2003 AprThis study found that taking creatine doesn’t change how muscles build or break down protein when you’re just sitting around. So if people get bigger muscles from creatine, it’s probably because they’re working out more, not because creatine is changing their muscles at rest.
Contradicting (0)
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Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.