If you swap out trans fats (like in fried foods) for healthy fats like those in fish or nuts, your risk of heart disease drops a lot—what you replace it with matters more than just cutting fat.
Scientific Claim
Replacing 2% of daily energy from trans fats with polyunsaturated fats is associated with a 24% lower risk of coronary heart disease, based on observational data from large cohort studies, suggesting nutrient substitution matters more than absolute fat intake.
Original Statement
“Replacement of 2% of energy from trans fats with polyunsaturated fat... was associated with a 24% (0.76, 0.67 to 0.85) reduction in CHD risk.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The claim correctly uses 'associated with' and references observational data. The authors explicitly discuss substitution effects and cite the 24% reduction as a derived insight from cohort data.
Evidence from Studies
Supporting (1)
Unknown Title
This study found that eating trans fats increases heart disease risk, but eating saturated fats doesn’t — so swapping bad fats (trans) for good ones (like polyunsaturated) likely helps your heart, even if total fat stays the same.