In women with polycystic ovary syndrome, a standardized extract of Asparagus racemosus root (CL22209) at a dose of 100 mg daily for 84 days is well-tolerated, with no clinically significant changes in haematological, biochemical, or safety parameters, and only mild transient adverse events similar to placebo.

The plant extract contains natural hormone-like substances. These substances bind to estrogen receptors in the brain and ovaries, which helps balance the hormones that control the menstrual cycle. The extract also makes the body more sensitive to insulin, which lowers blood sugar and reduces the production of male hormones. As a result, the ovaries work better and the cycle becomes regular. These changes happen through normal hormone pathways, so they do not harm blood cells, liver, or kidneys. This is why the treatment is safe and well-tolerated.